Rhupus Syndrome: An Overlap with Renal Complications

Rhupus Syndrome: An Overlap with Renal Complications

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Rhupus syndrome is a rare condition of overlap of Rheumatoid Arthritis (RA) and Systemic Lupus Erythematosus (SLE) H-SERIES PARTS presenting with erosive polyarthritis and symptoms of SLE.It occasionally has renal involvement as its complication makes the diagnosis more difficult.Here the authors present a case of a 13-year-old female with severe arthritis, which gradually progressed into lupus nephritis with the presence of specific autoantibodies confirming the Toys diagnosis of Rhupus.The child was managed with disease modifying anti-rheumatic drug (hydroxychloroquine), immunosuppressants (mycophenolate mofetil), steroid (prednisolone) and calcium channel blocker (amlodipine).

Accurate diagnosis is the key for early detection since Rhupus is a very rare disorder with very limited reported cases.